gtAI WorkflowΒΆ
- A reference set is obtained by taking 5% (or more) of coding sequences from a tested genome with the lowest ENc values (equation 3). (Or insert a reference set of interest)
- Then, RSCU values for the reference set are generated (equation 4).
- The genetic algorithm will search for the Sij weights that maximizes the correlation between (equation 1) and (equation 4).
- The final Wi values are calculated based on the optimized Sij weights from step 3.
- Calculated Wi values are normalized (wi), then the tAI value for a coding sequence (g) is calculated using equation 3.